PETdiatric UTI-OXI Urinary Nutraceutical 30 Tablets For Cats and Dogs
SKU: PD019
Category:
The highest content of PAC A on the market. PETdiatric Laboratories UTI-oxi uses the cranberry extract produced using a Biosfered Srl proprietary technology is first titrated with the DMAC method to obtain the total amount of PACs and subsequently is analyzed by liquid chromatography coupled to mass spectrometry (HPLC-ESI-MS/MS) for the assessment of the content of the PAC A (and the possible presence of PAC B).
The berries of cranberry are used since hundreds of years as a remedy for diseases of the urinary tract and have attracted attention due to their potential health benefits. The beneficial mechanism was historically thought to be due to the fruit acids causing a bacteriostatic effect in the urine. However, recently, a group of proanthocyanidins (PAC) with A-type linkages were isolated from cranberry which exhibit bacterial anti-adhesion activity against both antibiotic susceptible and resistant strains of uropathogenic P-fimbriated Escherichia coli bacteria. The phytochemicals associated with cranberry bioactivity include flavonoids, phenolic acid derivatives, hydroxycinnamic acid derivatives, organic acids, and isoprenoids (including ursolic acid and lutein). Among phenols are flavonols, anthocyanins and proanthocyanidins (PACs), catechins or flavan-3-ols.
Careful determination of the total PAC content using the BL-OMAC method and the authentication of PACs-A with mass spectrometry in cranberry extracts are necessary to prepare effective doses for UTI prevention . A dose of 112 mg UTI-oxi containing 36 mg PACs-A was found to be effective in preventing UTIs when used once per day for 7 days in animal less than 20kg.
Product description
PETdiatric Laboratories UTI-oxi is formulated with the highest content of PAC A on the market. Blended with a patented ingredient Oximacro®, it offers protection against bacterial adhesion and virulence in the urinary tract. Oximacro® is a cranberry extract characterized by a high content of Type A PACs which are the only proanthocyanidins bioactive against UTI.
UTI-oxi is to achieve an alternative non-antimicrobial therapeutic and/or prevention strategies for recurrent or persistent UTI in dogs and cats, in reducing the development of antimicrobial resistance and in achieving higher clinical success.
Recommended Use:
As a dietary supplement for protection and relieve of urinary tract irritation in canine and cats
Recommended dosage
Each tablet is to feed up to 20kg
21kg-40kg to take 2 tablet daily.
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